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Meanings of alkylators in English

Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning.

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        Examples for "alkylating agent"
        Examples for "alkylating agent"
        1
        All had previously received at least one purine analogue or alkylating agent.
        Pubmed
        2
        The role of hyperthermia during regional alkylating agent chemotherapy is controversial.
        Pubmed
        3
        Standard therapy for MM has been an alkylating agent and corticosteroid.
        Pubmed
        4
        Thiotepa is an alkylating agent widely used in high-dose chemotherapy.
        Pubmed
        5
        Treatment with this alkylating agent chemically compromises alkyl-DNA repair functions.
        Pubmed
        Usage of alkylators in English
        1
        HDAC inhibitors, DNA alkylators and nucleoside analogs are effective components of combination chemotherapy.
        Pubmed
        2
        On the other hand, the use of alkylators and topoisomerase II inhibitors is associated with an increased risk of t-AML.
        Pubmed
        3
        The protein level of MRP1 correlated with cellular resistance to busulfan and chlorambucil, and Rom exposure sensitized cells to these DNA alkylators.
        Pubmed
        4
        To determine a possible mechanism of their synergism, we analyzed the effects of HDAC inhibitors on the expression of drug transporters which export DNA alkylators.
        Pubmed
        Alkylators through the time